 |
| Cantidad: | |
|---|---|
DY9990
13710-19-5
237-264-3
C14H12ClNO2
tolfenamic acid
SPECIFICATION
White or slightly yellow, crystalline powder
Practically insoluble in water, soluble in dimethylformamide, sparingly soluble in ethanol and in methylene chloride
A. Light absorption: the ratio of the absorbance measured at the maximum at 286nm to that maximum at 345nm should be 1.2 to 1.4
B. IR absorption spectrophotometry should be conformed
C. TLC chromatography(254 nm) should be conformed
210 to 214 deg C
Impurity A 0.1% max; Impurity B 0.05% max;
Any other impurity 0.1% max
Total impurities 0.5% max
20ppm max
10ppm max
0.5% max
0.1% max
99.0% min
| INDEX NAME | SPECIFICATION |
| Description | White or slightly yellow, crystalline powder |
| Solubility | Practically insoluble in water, soluble in dimethylformamide, sparingly soluble in ethanol and in methylene chloride |
| Identification | A. Light absorption: the ratio of the absorbance measured at the maximum at 286nm to that maximum at 345nm should be 1.2 to 1.4 B. IR absorption spectrophotometry should be conformed C. TLC chromatography(254 nm) should be conformed |
| Melting Point | 210 to 214 deg C |
| Related substance | Impurity A 0.1% max; Impurity B 0.05% max; Any other impurity 0.1% max Total impurities 0.5% max |
| Heavy metals | 20ppm max |
| Copper | 10ppm max |
| Loss on drying | 0.5% max |
| Sulphated ash | 0.1% max |
| Assay(dried) | 99.0% min |
| INDEX NAME | SPECIFICATION |
| Description | White or slightly yellow, crystalline powder |
| Solubility | Practically insoluble in water, soluble in dimethylformamide, sparingly soluble in ethanol and in methylene chloride |
| Identification | A. Light absorption: the ratio of the absorbance measured at the maximum at 286nm to that maximum at 345nm should be 1.2 to 1.4 B. IR absorption spectrophotometry should be conformed C. TLC chromatography(254 nm) should be conformed |
| Melting Point | 210 to 214 deg C |
| Related substance | Impurity A 0.1% max; Impurity B 0.05% max; Any other impurity 0.1% max Total impurities 0.5% max |
| Heavy metals | 20ppm max |
| Copper | 10ppm max |
| Loss on drying | 0.5% max |
| Sulphated ash | 0.1% max |
| Assay(dried) | 99.0% min |